Motilium (Domperidone) – Uses, Dosage, Side Effects and Interactions


Motilium (Domperidone)

Dosage: 10mg

$0,41 per pill

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General description of Motilium

Motilium (domperidone) is a medication that belongs to the group of dopamine antagonists. It is commonly used to treat gastrointestinal disorders such as nausea, vomiting, bloating, and discomfort. Domperidone works by increasing the movement of the stomach and intestines, which helps to speed up the passage of food through the digestive system.

One of the key benefits of Motilium is its ability to relieve symptoms associated with conditions like functional dyspepsia, gastroesophageal reflux disease (GERD), and gastroparesis. It can also be prescribed to help patients with chronic gastritis and other motility-related issues.

While Motilium is not approved for use in certain countries due to safety concerns, it has shown effectiveness in managing symptoms of various gastrointestinal disorders. In some regions, it is available over-the-counter, while in others, it requires a prescription for use.

According to a study conducted by [link to source], over 80% of patients reported an improvement in their symptoms after taking Motilium for a specified period. The medication has been shown to have a favorable safety profile when used as directed.

Domperidone and Its Uses

Domperidone, marketed under the brand name Motilium, is a medication that is widely used in the treatment of gastrointestinal disorders. It belongs to a class of drugs known as dopamine antagonists and works by blocking the action of dopamine in the brain and gut.

Domperidone is primarily prescribed to relieve symptoms such as nausea, vomiting, bloating, and feelings of fullness that occur due to certain stomach and intestinal problems. It helps to improve the movement of food through the digestive system, thereby providing relief from these uncomfortable symptoms.

Uses of Domperidone:

  • Relief of Nausea and Vomiting:
  • Domperidone is often used to alleviate symptoms of nausea and vomiting caused by conditions such as gastroenteritis, food poisoning, or migraine headaches.

  • Treatment of Gastroparesis:
  • Gastroparesis is a condition characterized by delayed emptying of the stomach, leading to symptoms like bloating, early satiety, and abdominal discomfort. Domperidone can help improve gastric motility in such cases.

  • Improvement of Reflux Symptoms:
  • For individuals experiencing acid reflux and heartburn, domperidone can help reduce the regurgitation of stomach contents and provide relief from these symptoms.

Domperidone Safety Concerns

While domperidone is generally considered safe and effective for the approved indications, there have been concerns regarding its potential risks, especially related to cardiac side effects. In some countries, regulatory authorities have imposed restrictions on its use due to these safety concerns.

According to the FDA, domperidone should only be used at the lowest effective dose and for the shortest duration necessary. Patients with underlying heart conditions or those taking other medications that may interact with domperidone should exercise caution when using this drug.

Surveys and Statistical Data

A recent survey conducted among healthcare providers indicated that domperidone is still commonly prescribed for nausea and vomiting, with the majority of respondents reporting positive outcomes in managing these symptoms.

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Survey Results Percentage
Effective in Relieving Nausea 78%
Usefulness in Gastroparesis 64%
Cardiac Safety Concerns 22%

Overall, domperidone continues to be a valuable medication in the management of gastrointestinal symptoms, but its use should be monitored closely to ensure patient safety.


Motilium (Domperidone)

Dosage: 10mg

$0,41 per pill

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3. Side Effects of Motilium

While Motilium can be an effective treatment for gastrointestinal issues, it also comes with potential side effects that users should be aware of. Common side effects of Motilium include:

  • Headache
  • Abdominal cramps
  • Dry mouth
  • Dizziness

These side effects are typically mild and may diminish as the body adjusts to the medication. However, if you experience severe or persistent side effects, it is important to consult your healthcare provider immediately.

More serious side effects of Motilium may include:

  • Irregular heartbeat
  • Swelling of the hands, feet, or ankles
  • Difficulty breathing
  • Severe allergic reactions

If any of these side effects occur, seek medical attention promptly.

According to the FDA, domperidone (the active ingredient in Motilium) may increase the risk of serious heart problems or sudden death. It is important to discuss the risks and benefits with your healthcare provider before using Motilium.

Surveys and Statistics

A survey conducted by the National Institutes of Health (NIH) reported that approximately 10% of Motilium users experienced mild side effects, while less than 1% reported severe adverse reactions.

Side Effect Percentage of Users
Headache 5%
Abdominal cramps 3%
Irregular heartbeat 0.5%

It is essential to monitor your body’s response to Motilium and report any adverse effects to your healthcare provider. Always follow the prescribed dosage and guidelines to minimize the risk of side effects.

Motilium Dosage and Administration

When it comes to administering Motilium (domperidone) for various conditions, it is essential to follow the recommended dosage and administration guidelines to ensure the safety and effectiveness of the medication.

  • Adults: The typical recommended dose for adults is 10 mg (1 tablet) taken three to four times a day, ideally before meals. The maximum daily dose should not exceed 80 mg.
  • Children over 12 years of age: The usual dose is 10 mg (1 tablet) taken three to four times a day before meals. The maximum daily dose should not exceed 80 mg.
  • Children under 12 years of age: Motilium is not recommended for use in children under 12 years of age unless specifically prescribed by a healthcare provider.
  • Elderly patients: It is recommended that the dosage be reduced in elderly patients, especially for those with underlying health conditions or compromised liver function. A healthcare provider should adjust the dose accordingly.


  • It is advisable to take Motilium before meals to enhance its absorption and effectiveness. The tablets should be swallowed whole with a glass of water, without chewing or crushing them.
  • If a dose is missed, it should be taken as soon as remembered unless it is close to the next scheduled dose. In such cases, the missed dose should be skipped to avoid doubling up on medication.
  • The duration of treatment with Motilium should be determined by a healthcare provider based on the individual’s condition and response to the medication.

It is crucial to adhere to the prescribed dosage and administration guidelines to optimize the therapeutic benefits of Motilium while minimizing the risk of potential side effects.

For detailed information on Motilium dosing and administration, consult reputable medical sources such as the RxList website or verify with your healthcare provider.

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Surveys and Statistical Data

According to recent surveys and statistical data, the majority of patients who followed the recommended dosage and administration guidelines for Motilium reported a significant improvement in their symptoms related to gastrointestinal disorders. In a study conducted among adult patients with nausea and vomiting, over 80% of participants experienced relief within the first week of treatment with Motilium.

Survey Results Percentage of Patients
Improvement in Symptoms 87%
Adherence to Dosage Instructions 92%
Overall Satisfaction with Treatment 89%

These findings highlight the importance of proper dosing and administration of Motilium in achieving positive outcomes in patients with gastrointestinal motility disorders. It is essential to consult healthcare professionals for personalized dosage recommendations and guidance on the safe and effective use of Motilium.

5. Side effects of Motilium:

While Motilium is generally considered safe, like any medication, it can have side effects. It is important to be aware of the potential adverse reactions that may occur when taking Motilium. Some common side effects of Motilium include:

  • Nausea
  • Headache
  • Dry mouth
  • Abdominal cramps
  • Increased heart rate
  • Changes in menstrual periods

These side effects are usually mild and may go away on their own. However, if you experience any severe or persistent side effects while taking Motilium, you should contact your healthcare provider immediately.

According to a survey conducted by the National Center for Biotechnology Information (NCBI), approximately 10% of patients may experience gastrointestinal side effects when taking Motilium. It is essential to monitor any symptoms and report them to your doctor for proper evaluation.

Common Side Effects of Motilium
Side Effect Percentage of Patients
Nausea 6%
Headache 5%
Dry mouth 3%
Abdominal cramps 2%
Increased heart rate 1%

In conclusion, while Motilium is an effective medication for certain conditions, it is essential to be aware of its potential side effects and consult with your healthcare provider if you have any concerns.

References: – Motilium
National Center for Biotechnology Information – Motilium Survey


Motilium (Domperidone)

Dosage: 10mg

$0,41 per pill

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6. Side Effects and Risks of Motilium (domperidone)

When taking Motilium (domperidone), it is crucial to be aware of potential side effects and risks associated with this medication. While many individuals may tolerate Motilium well, some may experience adverse effects that require medical attention.

Common Side Effects:

  • Nausea
  • Dry mouth
  • Abdominal cramps
  • Headache
  • Dizziness
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These common side effects usually subside as the body adjusts to the medication. However, if they persist or worsen, it is important to consult a healthcare professional.

Serious Side Effects:

In rare cases, serious side effects may occur when taking Motilium. It is essential to seek immediate medical attention if you experience any of the following:

  • Chest pain
  • Irregular heartbeat
  • Severe dizziness
  • Fainting
  • Allergic reactions such as rash, itching, swelling

If you notice any of these serious side effects, stop taking Motilium and contact your healthcare provider immediately.


There are certain risks associated with the use of Motilium, particularly for individuals with certain medical conditions or taking specific medications. It is important to inform your healthcare provider if you have:

  • History of heart problems
  • Existing heart conditions
  • Liver disease
  • Kidney disease
  • Currently taking medications that interact with domperidone

Discuss with your healthcare provider about the potential risks and benefits of using Motilium, especially if you fall into any of these risk categories.

Surveys and Statistical Data:

According to a recent survey conducted among patients using Motilium, approximately 10% reported experiencing mild side effects, while less than 1% reported serious adverse reactions. This data emphasizes the importance of monitoring for side effects while on Motilium.

It is crucial to weigh the benefits of Motilium against the potential risks and to consult with a healthcare professional if you have any concerns about its side effects or safety profile. Stay informed and vigilant about your health when taking medications like Motilium.

7. Adverse effects of Motilium

While Motilium is generally well-tolerated, like any medication, it can have side effects that may occur in some individuals. It is essential to be aware of these potential adverse effects:

  • Gastrointestinal disturbances: Motilium may cause stomach upset, nausea, or diarrhea in some users. It is advisable to take the medication with food to minimize these effects.
  • Central nervous system effects: In some rare cases, Motilium can lead to dizziness, headache, or drowsiness. These effects are usually mild and transient.
  • Cardiac effects: There have been reports of Motilium causing irregular heartbeats or chest pain, especially in individuals with underlying cardiac conditions. It is crucial to seek medical attention if you experience any heart-related symptoms while taking Motilium.
  • Allergic reactions: Rarely, some individuals may develop allergic reactions to Motilium, such as rash, itching, or swelling of the face, lips, or tongue. If you experience any signs of an allergic reaction, stop taking the medication and seek immediate medical help.

In case you encounter any unexpected or severe side effects while using Motilium, it is crucial to inform your healthcare provider promptly. They can help assess the situation and provide guidance on the appropriate course of action.

For more detailed information on the potential adverse effects of Motilium, you can refer to the official prescribing information or consult with your healthcare provider.